As if driven by an inescapable force, Isabel (Michelle Williams) has devoted her life to running an orphanage in a Calcutta slum. With funds running dry, a potential donor appears, requiring Isabelle to travel from India to New York. The city she deliberately hasn't returned to in over two decades.
Once in New York, Isabel meets the orphanage's possible benefactor, Theresa Young (Julianne Moore), a multi-millionaire media mogul accustomed to getting what she wants. From the glittering skyscraper where she runs her successful business, to the glorious Oyster Bay estate, where she lives happily with her artist husband, Oscar Carlson (Billy Crudup), 21-year-old daughter, Grace (Abby Quinn), and eight-year-old twins, Theo and Otto, Theresa's life couldn't appear to be more perfect and different from Isabel’s. But appearances are only skin deep and the two women have more in common than meets the eye.
While Isabel thinks she'll immediately be returning to her beloved orphanage, Theresa has other plans, insisting Isabel attend Grace's wedding at the family's estate. The joyful event becomes a catalyst for a revelation that upends the lives of both women.